Podocyte depletion drives kidney disease and kidney failure progression, but podocyte complexity at the glomerular filtration barrier is difficult to model in vitro. In Nature Biomedical Engineering, Musah et al. (2017) developed a multifluidic device with iPS-derived podocytes mimicking a functional glomerular filtration barrier that elevates standards for modeling glomerular diseases.
Modeling the Glomerular Filtration Barrier: Are You Kidney-ing Me? / Romagnani, P, Lasagni L.. - In: CELL STEM CELL. - ISSN 1934-5909. - ELETTRONICO. - 21:(2017), pp. 7-9. [10.1016/j.stem.2017.06.008]
Modeling the Glomerular Filtration Barrier: Are You Kidney-ing Me?
Romagnani P
;Lasagni L.
2017
Abstract
Podocyte depletion drives kidney disease and kidney failure progression, but podocyte complexity at the glomerular filtration barrier is difficult to model in vitro. In Nature Biomedical Engineering, Musah et al. (2017) developed a multifluidic device with iPS-derived podocytes mimicking a functional glomerular filtration barrier that elevates standards for modeling glomerular diseases.
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