Preoperative Renal Functional Reserve Predicts Risk of Acute Kidney Injury After Cardiac Surgery

Husain-Syed, Faeq; Ferrari, Fiorenza; Sharma, Aashish; Hinna Danesi, Tommaso; Bezerra, Pércia; Lopez-Giacoman, Salvador; Samoni, Sara; de Cal, Massimo; Corradi, Valentina; Virzì, Grazia Maria; De Rosa, Silvia; Muciño Bermejo, María Jimena; Estremadoyro, Carla; Villa, Gianluca; Zaragoza, Jose J; Caprara, Carlotta; Brocca, Alessandra; Birk, Horst-Walter; Walmrath, Hans-Dieter; Seeger, Werner; Nalesso, Federico; Zanella, Monica; Brendolan, Alessandra; Giavarina, Davide; Salvador, Loris; Bellomo, Rinaldo; Rosner, Mitchell H; Kellum, John A; Ronco, Claudio

doi:10.1016/j.athoracsur.2017.12.034

Although acute kidney injury (AKI) frequently complicates cardiac surgery, methods to determine AKI risk in patients without underlying kidney disease are lacking. Renal functional reserve (RFR) can be used to measure the capacity of the kidney to increase glomerular filtration rate under conditions of physiological stress and may serve as a functional marker that assesses susceptibility to injury. We sought to determine whether preoperative RFR predicts postoperative AKI.

Preoperative Renal Functional Reserve Predicts Risk of Acute Kidney Injury After Cardiac Surgery / Husain-Syed, Faeq; Ferrari, Fiorenza; Sharma, Aashish; Hinna Danesi, Tommaso; Bezerra, Pércia; Lopez-Giacoman, Salvador; Samoni, Sara; de Cal, Massimo; Corradi, Valentina; Virzì, Grazia Maria; De Rosa, Silvia; Muciño Bermejo, María Jimena; Estremadoyro, Carla; Villa, Gianluca; Zaragoza, Jose J; Caprara, Carlotta; Brocca, Alessandra; Birk, Horst-Walter; Walmrath, Hans-Dieter; Seeger, Werner; Nalesso, Federico; Zanella, Monica; Brendolan, Alessandra; Giavarina, Davide; Salvador, Loris; Bellomo, Rinaldo; Rosner, Mitchell H; Kellum, John A; Ronco, Claudio. - In: ANNALS OF THORACIC SURGERY. - ISSN 0003-4975. - ELETTRONICO. - (2018), pp. 1094-1101. [10.1016/j.athoracsur.2017.12.034]