We report the multiple detection of Proteus mirabilis isolates, from 4 different long-term care and rehabilitation facilities (LTCRFs) of Northern Italy, resistant to expanded-spectrum cephalosporins and cephamycins and producing an acquired ampC-like beta-lactamase, named CMY-16. Genotyping by PFGE showed that isolates were clonally related to each other, although not identical. In all isolates the bla(CMY16) gene was not transferable by conjugation and was found to be carried on the chromosome. These results revealed multifocal spreading of a CMY-16 producing P. mirabilis clone in Northern Italy and emphasize the emergence of similar acquired resistance determinants in the LTCRFs setting.

Acquired AmpC type beta-lactamases: an emerging problem in Italian long-term care and rehabilitation facilities / Migliavacca, Roberta; Nucleo, Elisabetta; D'Andrea, Marco M; Spalla, Melissa; Giani, Tommaso; Pagani, Laura. - In: NEW MICROBIOLOGICA. - ISSN 1121-7138. - ELETTRONICO. - 30:(2007), pp. 295-298.

Acquired AmpC type beta-lactamases: an emerging problem in Italian long-term care and rehabilitation facilities

D'Andrea, Marco M;Giani, Tommaso;
2007

Abstract

We report the multiple detection of Proteus mirabilis isolates, from 4 different long-term care and rehabilitation facilities (LTCRFs) of Northern Italy, resistant to expanded-spectrum cephalosporins and cephamycins and producing an acquired ampC-like beta-lactamase, named CMY-16. Genotyping by PFGE showed that isolates were clonally related to each other, although not identical. In all isolates the bla(CMY16) gene was not transferable by conjugation and was found to be carried on the chromosome. These results revealed multifocal spreading of a CMY-16 producing P. mirabilis clone in Northern Italy and emphasize the emergence of similar acquired resistance determinants in the LTCRFs setting.
2007
30
295
298
Migliavacca, Roberta; Nucleo, Elisabetta; D'Andrea, Marco M; Spalla, Melissa; Giani, Tommaso; Pagani, Laura
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1112702
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