Polymer nanogels are embedded within layers consisting of a nonlamellar liquid crystalline lipid phase to act as thermoresponsive controllers of layer compactness and hydration. As the nanogels change from the swollen to the collapsed state via a temperature trigger, they enable on-demand release of water from the mixed polymer-lipid layer while the lipid matrix remains intact. Combining stimuli-responsive polymers with responsive lipid-based mesophase systems opens up new routes in biomedical applications such as functional biomaterials, bioanalysis and drug delivery.
Temperature responsive lipid liquid crystal layers with embedded nanogels / Dabkowska, A.P.*; Hirst, C.; Valldeperas, M.; Clifton, L.A.; Montis, C.; Nöjd, S.; Gentile, L.; Wang, M.; Pálsson, G.K.; Lages, S.; Berti, D.; Barauskas, J.; Nylander, T.. - In: CHEMICAL COMMUNICATIONS. - ISSN 1359-7345. - STAMPA. - 53:(2017), pp. 1417-1420. [10.1039/c6cc09426k]
Temperature responsive lipid liquid crystal layers with embedded nanogels
Montis, C.;Berti, D.;
2017
Abstract
Polymer nanogels are embedded within layers consisting of a nonlamellar liquid crystalline lipid phase to act as thermoresponsive controllers of layer compactness and hydration. As the nanogels change from the swollen to the collapsed state via a temperature trigger, they enable on-demand release of water from the mixed polymer-lipid layer while the lipid matrix remains intact. Combining stimuli-responsive polymers with responsive lipid-based mesophase systems opens up new routes in biomedical applications such as functional biomaterials, bioanalysis and drug delivery.
I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
