Rhein (R), 4,5-diacetylrhein (DAR), 4,5-dipropionylrhein (DPR) and 4,5-dibenzoyl-rhein (DBR) were studied in vitro against certain proteases (pepsin, trypsin, carboxypeptidase A, elastase) and compared to ɛ-aminocaproic acid and to aprotinin. Rhein and its derivatives inhibit the protease in the range of 10−4 – 10−5M concentrations.
Rhein and derivates. In vitro studies on their capacity to inhibit certain proteases / Raimondi L, Banchelli Soldaini G, Buffoni F, Ignesti G, Massacesi L, Amaducci L, Friedmann CA.. - In: PHARMACOLOGICAL RESEARCH COMMUNICATIONS. - ISSN 0031-6989. - STAMPA. - 14:(1982), pp. 103-112.
Rhein and derivates. In vitro studies on their capacity to inhibit certain proteases.
Raimondi L;Buffoni F;Ignesti G;Massacesi L;Amaducci L;
1982
Abstract
Rhein (R), 4,5-diacetylrhein (DAR), 4,5-dipropionylrhein (DPR) and 4,5-dibenzoyl-rhein (DBR) were studied in vitro against certain proteases (pepsin, trypsin, carboxypeptidase A, elastase) and compared to ɛ-aminocaproic acid and to aprotinin. Rhein and its derivatives inhibit the protease in the range of 10−4 – 10−5M concentrations.File in questo prodotto:
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