The present invention relates to a compound comprising a protected or deprotected thiol moiety S enabling Native Chemical Ligation, a photolabile linker moiety L and at least one hydrophilic polymer moiety HP. Furthermore, the present invention relates to a method for production of a peptide conjugate P12 comprising a peptide moiety P1 and a second moiety P2 covalently bound with another via an amide bond, wherein the compound of the present invention employed for selectively forming the amide bond between P1 and P2.
A compound for preparing polypeptides / Christian Friederich Wilhelm Becker; Claudia Bello. - (2016).
A compound for preparing polypeptides
Claudia Bello
2016
Abstract
The present invention relates to a compound comprising a protected or deprotected thiol moiety S enabling Native Chemical Ligation, a photolabile linker moiety L and at least one hydrophilic polymer moiety HP. Furthermore, the present invention relates to a method for production of a peptide conjugate P12 comprising a peptide moiety P1 and a second moiety P2 covalently bound with another via an amide bond, wherein the compound of the present invention employed for selectively forming the amide bond between P1 and P2.
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