The cellular origins of angiomyolipoma and other tuberous sclerosis complex-associated neoplasms are unknown. Now, two studies show that these neoplasms derive from cancer stem cells that originate from multipotent renal epithelial cells. The new findings provide a link between stemness and tumorigenesis in the kidney.
Angiomyolipoma: A link between stemness and tumorigenesis in the kidney / Paola Romagnani. - In: NATURE REVIEWS. NEPHROLOGY. - ISSN 1759-5061. - STAMPA. - 14:(2018), pp. 215-216. [10.1038/nrneph.2018.16]
Angiomyolipoma: A link between stemness and tumorigenesis in the kidney.
Paola Romagnani
Writing – Review & Editing
2018
Abstract
The cellular origins of angiomyolipoma and other tuberous sclerosis complex-associated neoplasms are unknown. Now, two studies show that these neoplasms derive from cancer stem cells that originate from multipotent renal epithelial cells. The new findings provide a link between stemness and tumorigenesis in the kidney.
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