Chromatic pupillometry is a relatively novel research tool for the evaluation of retina function and may be a novel way to diagnose and monitor inherited retinal diseases in paediatric population. Nevertheless, although the method is clinically feasible in paediatric populations, as shown by several non-ocular studies, only few studies, on a small size sample of paediatric ophthalmic subjects, are available. Moreover, to the best of the authors’ knowledge, no medical device based on chromatic pupillometry was CE-marked for diagnosis and / or monitoring of inherited ocular disease. Therefore, we designed a pilot study in order to evaluate clinical feasibility and utility of chromatic pupillometry. The study sample consists of sixty patients, affected by inherited ocular diseases. A pupillometric system, including definition of pupillometric protocols, have been set up. In the current paper, we present the comparison between the measurements obtained in one patient affected by Retinitis Pigmentosa and a healthy age-matched control in order to show the differences in chromatic pu-pillometry parameters between case and control.
Toward a Novel Medical Device Based on Chromatic Pupillometry for Screening and Monitoring of Inherited Ocular Disease: A Pilot Study / Melillo, Paolo; de Benedictis, Antonella; Villani, Edoardo; Ferraro, Maria Concetta; Iadanza, Ernesto; Gherardelli, Monica; Testa, Francesco; Banfi, Sandro; Nucci, Paolo; Simonelli, Francesca. - ELETTRONICO. - 68/3:(2019), pp. 387-390. (Intervento presentato al convegno World Congress on Medical Physics and Biomedical Engineering 2018 tenutosi a Praga nel June 3-8, 2018) [10.1007/978-981-10-9023-3_70].
Toward a Novel Medical Device Based on Chromatic Pupillometry for Screening and Monitoring of Inherited Ocular Disease: A Pilot Study
Iadanza, Ernesto;Gherardelli, Monica;
2019
Abstract
Chromatic pupillometry is a relatively novel research tool for the evaluation of retina function and may be a novel way to diagnose and monitor inherited retinal diseases in paediatric population. Nevertheless, although the method is clinically feasible in paediatric populations, as shown by several non-ocular studies, only few studies, on a small size sample of paediatric ophthalmic subjects, are available. Moreover, to the best of the authors’ knowledge, no medical device based on chromatic pupillometry was CE-marked for diagnosis and / or monitoring of inherited ocular disease. Therefore, we designed a pilot study in order to evaluate clinical feasibility and utility of chromatic pupillometry. The study sample consists of sixty patients, affected by inherited ocular diseases. A pupillometric system, including definition of pupillometric protocols, have been set up. In the current paper, we present the comparison between the measurements obtained in one patient affected by Retinitis Pigmentosa and a healthy age-matched control in order to show the differences in chromatic pu-pillometry parameters between case and control.File | Dimensione | Formato | |
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