The transgenic D1CT-7 mouse is one of the best-characterized animal models of Tourette's syndrome (TS), exhibiting spontaneous tic-like Head-Body Twitches (HBT) and deficits in sensorimotor gating. This study is aimed at evaluating the behavioral dynamics of these mutants and their potential relevance to TS.
Behavioral fragmentation in the D1CT-7 mouse model of Tourette's syndrome / Santangelo A, Bortolato M, Mosher LJ, Crescimanno G, Di Giovanni G, Cassioli E, Ricca V, Casarrubea M. - In: CNS NEUROSCIENCE & THERAPEUTICS. - ISSN 1755-5930. - ELETTRONICO. - (2018), pp. 703-711.
Behavioral fragmentation in the D1CT-7 mouse model of Tourette's syndrome
SANTANGELO, ANDREA;CASSIOLI, EMANUELE;Ricca V;
2018
Abstract
The transgenic D1CT-7 mouse is one of the best-characterized animal models of Tourette's syndrome (TS), exhibiting spontaneous tic-like Head-Body Twitches (HBT) and deficits in sensorimotor gating. This study is aimed at evaluating the behavioral dynamics of these mutants and their potential relevance to TS.
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