The Nociceptin/Orphanin FQ (N/OFQ) peptide NOP receptor is coupled to pertussis toxin (PTX)-sensitive G proteins (Gi/o) whose activation leads to the inhibition of both cAMP production and calcium channel activity, and to the stimulation of potassium currents.
NOP receptor pharmacological profile - A dynamic mass redistribution study / Malfacini D, Simon K, Trapella C, Guerrini R, Zaveri NT, Kostenis E, Calo' G.. - In: PLOS ONE. - ISSN 1932-6203. - ELETTRONICO. - 13:(2018), pp. 20-21. [10.1371/journal.pone.0203021]
NOP receptor pharmacological profile - A dynamic mass redistribution study
Calo' G.
2018
Abstract
The Nociceptin/Orphanin FQ (N/OFQ) peptide NOP receptor is coupled to pertussis toxin (PTX)-sensitive G proteins (Gi/o) whose activation leads to the inhibition of both cAMP production and calcium channel activity, and to the stimulation of potassium currents.File in questo prodotto:
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