Maintenance therapy following autologous stem cell transplantation (ASCT) can delay disease progression and prolong survival in patients with multiple myeloma. Ixazomib is ideally suited for maintenance therapy given its convenient once-weekly oral dosing and low toxicity profile. In this study, we aimed to determine the safety and efficacy of ixazomib as maintenance therapy following ASCT.

Oral ixazomib maintenance following autologous stem cell transplantation (TOURMALINE-MM3): a double-blind, randomised, placebo-controlled phase 3 trial / Dimopoulos, Meletios A; Gay, Francesca; Schjesvold, Fredrik; Beksac, Meral; Hajek, Roman; Weisel, Katja Christina; Goldschmidt, Hartmut; Maisnar, Vladimir; Moreau, Philippe; Min, Chang Ki; Pluta, Agnieszka; Chng, Wee-Joo; Kaiser, Martin; Zweegman, Sonja; Mateos, Maria-Victoria; Spencer, Andrew; Iida, Shinsuke; Morgan, Gareth; Suryanarayan, Kaveri; Teng, Zhaoyang; Skacel, Tomas; Palumbo, Antonio; Dash, Ajeeta B; Gupta, Neeraj; Labotka, Richard; Rajkumar, S Vincent, Bosi a. - In: THE LANCET. - ISSN 0140-6736. - STAMPA. - (2018), pp. 207-211. [10.1016/S0140-6736(18)33003-4]

Oral ixazomib maintenance following autologous stem cell transplantation (TOURMALINE-MM3): a double-blind, randomised, placebo-controlled phase 3 trial

Bosi a
2018

Abstract

Maintenance therapy following autologous stem cell transplantation (ASCT) can delay disease progression and prolong survival in patients with multiple myeloma. Ixazomib is ideally suited for maintenance therapy given its convenient once-weekly oral dosing and low toxicity profile. In this study, we aimed to determine the safety and efficacy of ixazomib as maintenance therapy following ASCT.
2018
207
211
Dimopoulos, Meletios A; Gay, Francesca; Schjesvold, Fredrik; Beksac, Meral; Hajek, Roman; Weisel, Katja Christina; Goldschmidt, Hartmut; Maisnar, Vlad...espandi
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1145700
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