In this work we applied a single molecule technique to investigate an intriguing biological problem not yet fully understood. We used a novel approach capable to measure with unprecedent spatial and temporal precision the interaction between proteins and DNA, allowing us to determine the position of both specific and unspecific interaction along the DNA filament.
Mapping DNA-LAC repressor interaction with ultra-fast optical tweezer / Monico, C.; Pavone, F.S.; Tempestini, A.; Vanzi, F.; Capitanio, M.. - ELETTRONICO. - (2015), pp. 3 .-3 .. (Intervento presentato al convegno 2015 Fotonica AEIT Italian Conference on Photonics Technologies) [10.1049/cp.2015.0172].
Mapping DNA-LAC repressor interaction with ultra-fast optical tweezer
FERREIRA MONICO, CARINA ISABEL;Pavone, F. S.;TEMPESTINI, ALESSIA;Vanzi, F.;Capitanio, M.
2015
Abstract
In this work we applied a single molecule technique to investigate an intriguing biological problem not yet fully understood. We used a novel approach capable to measure with unprecedent spatial and temporal precision the interaction between proteins and DNA, allowing us to determine the position of both specific and unspecific interaction along the DNA filament.
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