Diagnostic imaging of gastrointestinal neuroendocrine tumours (GI-NETs): relationship between MDCT features and 2010 WHO classification. Grazzini G, Danti G, Cozzi D, Lanzetta MM, Addeo G, Falchini M, Masserelli A, Pradella S, Miele V. Radiol Med. Feb;124(2):94-102. doi: 10.1007/s11547-018-0946-8. Epub 2018 Sep 25.

We aimed to present a series of gastrointestinal neuroendocrine tumours (GI-NETs) in order to illustrate and highlight the associated contrast-enhanced multi-detector computed tomography (MDCT) features. We attempted to identify a relationship between MDCT imaging and the 2010 World Health Organization (WHO) classification system. MATERIALS AND METHODS: We selected all patients with pathologically proven GI-NETs diagnosed between January 2010 and August 2017. Only patients undergone contrast-enhanced MDCT imaging in the immediate preoperative period were included in our study. Later, two expert radiologists retrospectively assessed MDCT intestinal and extra-intestinal signs. We also analysed the relationship between MDCT imaging and the 2010 WHO classification. CONCLUSIONS: The majority of GI-NETs appears as intraluminal mass often associated with extra-intestinal signs. We found a significantly correlation between higher grade of GI-NETs and extra-intestinal signs. MDCT imaging may be useful in predicting the pathological classification of GI-NETs.