Testosterone and Breast Cancer in Transmen

Limited information exists regarding breast health in the transgender population.The incidence of breast cancer in transmen is very rare and only a few cases have been described in the literature. Nonetheless, a correlation between high dosage of testosterone and risk of breast cancer has been postulated. This is a very important issue within the health care of transgender people.Our experience is with 80 transmen who underwent top surgery to create an aesthetically pleasing male chest. Only in 2 of them we identified breast cancer. The first diagnosis was before top surgery, the second one was an occasional histological finding.It is important to bear in mind all of the complex relationships between testosterone therapy and breast cancer. It is necessary to inform transgender persons, especially those who have not yet undergone top surgery, of risk factors for breast cancer and the potential risk of developing a breast cancer, about the importance of selecting the most appropriate surgical technique according to the patient's risk and preferences, and to perform accurate postoperative surveillance.A multidisciplinary approach to these patients is strongly recommended, and large database creation and networking is warranted. (C) 2018 Elsevier Inc. All rights reserved.

Testosterone and Breast Cancer in Transmen: Case Reports, Review of the Literature, and Clinical Observation / Tanini S, Fisher AD, Meattini I, Bianchi S, Ristori J, Maggi M, Lo Russo G. - In: CLINICAL BREAST CANCER. - ISSN 1526-8209. - ELETTRONICO. - 19:2(2019), pp. E271-E275. [10.1016/j.clbc.2018.12.006]

Testosterone and Breast Cancer in Transmen: Case Reports, Review of the Literature, and Clinical Observation

Tanini S;Fisher AD;Meattini I;Bianchi S;Ristori J;Maggi M;Lo Russo G
2019

Abstract

Limited information exists regarding breast health in the transgender population.The incidence of breast cancer in transmen is very rare and only a few cases have been described in the literature. Nonetheless, a correlation between high dosage of testosterone and risk of breast cancer has been postulated. This is a very important issue within the health care of transgender people.Our experience is with 80 transmen who underwent top surgery to create an aesthetically pleasing male chest. Only in 2 of them we identified breast cancer. The first diagnosis was before top surgery, the second one was an occasional histological finding.It is important to bear in mind all of the complex relationships between testosterone therapy and breast cancer. It is necessary to inform transgender persons, especially those who have not yet undergone top surgery, of risk factors for breast cancer and the potential risk of developing a breast cancer, about the importance of selecting the most appropriate surgical technique according to the patient's risk and preferences, and to perform accurate postoperative surveillance.A multidisciplinary approach to these patients is strongly recommended, and large database creation and networking is warranted. (C) 2018 Elsevier Inc. All rights reserved.
2019
19
E271
E275
Testosterone and Breast Cancer in Transmen
Tanini S, Fisher AD, Meattini I, Bianchi S, Ristori J, Maggi M, Lo Russo G
File in questo prodotto:
File Dimensione Formato  
FISHER ET AL., 2019.pdf

Accesso chiuso

Tipologia: Pdf editoriale (Version of record)
Licenza: Tutti i diritti riservati
Dimensione 854.92 kB
Formato Adobe PDF
854.92 kB Adobe PDF   Richiedi una copia

I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1151191
Citazioni
  • ???jsp.display-item.citation.pmc??? 3
  • Scopus 21
  • ???jsp.display-item.citation.isi??? 19
social impact