The occurrence of intraoperative complications during partial nephrectomy and their impact on postoperative outcome: Results from the RECORd1 project

Background: The aim of this study was to analyze the predictive factors of intraoperative complications in patients submitted to PN and the impact of intraoperative complications on postoperative outcomes. MeTHoDS: Data of 1055 patients who underwent PN for cortical renal masses were recorded from a multicenter prospective observational study (record1 project). reSUlTS: overall, 48 (5%) patients experienced 49 intraoperative complications (four medical, 45 surgical). at multi- variable analysis, age (or=1.02, 95% ci: 1.00-1.08, P=0.03), imperative versus elective surgical indication (or=2.55, 95% ci: 1.12-5.85, P=0.03), open (or=5.76, 95% ci: 1.05-9.21, P=0.01) and laparoscopic (or=2.35, 95% ci: 1.11- 4.95, P=0.03) versus robotic approaches resulted independent predictive factors of intraoperative complications. Patients experiencing intraoperative complications had a significantly higher rate of overall postoperative complications (41.6% vs. 17.3%, P<0.0001), surgical postoperative complications (29.2% vs. 12.6%, P<0.0001), clavien 2 surgical postoperative complications (14.6% vs. 7.2%, P=0.05) and a significantly longer length of stay (8 [6-9] vs. 7 [5-8] days, P<0.0001) than those with an uneventful intraoperative course. coNclUSioNS: efforts should be made to minimize the risk of intraoperative complications during PN, and, in that case, patients should be carefully monitored.