PD66-09 ACCURATE PREDICTION OF PROGRESSION TO MUSCLE INVASIVE DISEASE IN PATIENTS WITH T1G3 BLADDER CANCER: A CLINICAL DECISION-MAKING TOOL

Current prognostic models for urinary bladder cancer (UBC) are still suboptimal in identifying patients with non-invasive disease who are more likely to progress to muscle invasive bladder cancer (MIBC). Lymphovascular invasion (LVI) and variant histology (VH) are adverse pathologic features that could help identifying these patients, supporting counselling for early radical cystectomy (RC). We demonstrated the clinical value of the integration of LVI and VH in a prognostic model for the prediction of MIBC. Indeed, our tool provides superior individualized risk estimation of progression facilitating decision-making regarding early RC.