Inorganic CsPbBr3 perovskite devices have been manufactured and tested as dosimeters under both conventional and Intensity Modulated Radiotherapy (IMRT) X-ray beams. Samples showed a very good linear dependence of the collected charge/current on dose/dose rates in the range of 0.1–5.0 Gy/0.1–4.0 Gy/min of interest for clinical applications. A device sensitivity of about 70 nC/Gy mm3 compares favorably with other solid-state dosimeters. The first verification of an IMRT dose profile of a prostate cancer treatment, performed by moving the perovskite device on a 10 cm-long profile with a 0.5 mm pitch, showed agreement within 5% with the dose distribution required by the treatment planning system.
First proof-of-principle of inorganic perovskites clinical radiotherapy dosimeters / Bruzzi, Mara; Talamonti, Cinzia; Calisi, Nicola; Caporali, Stefano; Vinattieri, Anna. - In: APL MATERIALS. - ISSN 2166-532X. - ELETTRONICO. - 7:(2019), pp. 051101-051107. [10.1063/1.5083810]
First proof-of-principle of inorganic perovskites clinical radiotherapy dosimeters
Bruzzi, Mara;Talamonti, Cinzia;Calisi, Nicola;Caporali, Stefano;Vinattieri, Anna
2019
Abstract
Inorganic CsPbBr3 perovskite devices have been manufactured and tested as dosimeters under both conventional and Intensity Modulated Radiotherapy (IMRT) X-ray beams. Samples showed a very good linear dependence of the collected charge/current on dose/dose rates in the range of 0.1–5.0 Gy/0.1–4.0 Gy/min of interest for clinical applications. A device sensitivity of about 70 nC/Gy mm3 compares favorably with other solid-state dosimeters. The first verification of an IMRT dose profile of a prostate cancer treatment, performed by moving the perovskite device on a 10 cm-long profile with a 0.5 mm pitch, showed agreement within 5% with the dose distribution required by the treatment planning system.File | Dimensione | Formato | |
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