We analyzed the clinical utility of molecular classification based on anatomical and histological background. The study was conducted on 457 patients treated for gastric cancer with additional information about microsatellite instability status. We divided the patients in three groups of molecular classification based on anatomical and histological background: proximal non-diffused, diffused, and distal non-diffused groups. These groups varied in terms of clinical and pathological factors as well as survival rates. The molecular classification based on anatomical and histological data seems to be a useful tool in a simple classification of gastric cancer.
Single Center Experience on Anatomy-and Histopathology-Based Gastric Cancer Molecular Classification / Polom, Karol; Marrelli, Daniele; ROVIELLO, GIANDOMENICO; Voglino, Costantino; Vindigni, Carla; GENERALI, DANIELE; Roviello, Franco. - In: CANCER INVESTIGATION. - ISSN 0735-7907. - STAMPA. - 35:(2017), pp. 325-332. [10.1080/07357907.2017.1292519]
Single Center Experience on Anatomy-and Histopathology-Based Gastric Cancer Molecular Classification
ROVIELLO, GIANDOMENICO;
2017
Abstract
We analyzed the clinical utility of molecular classification based on anatomical and histological background. The study was conducted on 457 patients treated for gastric cancer with additional information about microsatellite instability status. We divided the patients in three groups of molecular classification based on anatomical and histological background: proximal non-diffused, diffused, and distal non-diffused groups. These groups varied in terms of clinical and pathological factors as well as survival rates. The molecular classification based on anatomical and histological data seems to be a useful tool in a simple classification of gastric cancer.File | Dimensione | Formato | |
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CANCER INVEST 2017 MOLECULAR CLASS.pdf
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