URODYNAMIC STUDIES IN PATIENTS UNDERGONE SEX REASSIGNMENT SURGERY: PRE AND POSTOPERATIVE ASSESSMENT IN MALE TO FEMALE PATIENTS

Transgender patients with Male to Female (MtF) Gender Dysphoria (GD) require multidisciplinary assessment and management. The Feminizing Hormone Therapy (FHT) and Sex Reassignment Surgery (SRS) are the cornerstone of treatment of MtF patients. The FHT includes the use of Progynova® (estradiol valerate) and Androcur® (cyproterone acetate) for at least 12 continuous months before SRS. The SRS consists in vaginoplasty and is composed of orchiectomy, penile disassembly, creation of a neovaginal cavity, repositioning of urethral meatus and neoclitorolabioplasty. The creation of the neovaginal cavity partially involves the mechanism of urinary continence because it demolishes the posterior part of the trigonal portion of the striated (external) urinary sphincter. For these reasons the aim of our study is to assess prospectively the effects of FHT and SRS on lower urinary tract (LUT) function.