Intravenous immunoglobulins are the cornerstone for the treatment of primary humoral immunodeficiencies and may be used for a great number of other autoimmune, neurological and hematological conditions as well. Given their wide application, the possibility of running across a patient who needs this kind of therapy is becoming increasingly common. Generally, intravenous immunoglobulins are well tolerated. However, numerous adverse reactions ranging from mild to severe have been reported and linked to patient- and product-related factors. For all these reasons, we present herein a comprehensive review of the on- and off-label applications of intravenous immunoglobulins and provide a guide for the internist how to minimize the risk of adverse reactions and manage them.

Intravenous immunoglobulin therapy: a snapshot for the internist / Vitiello Gianfranco, Emmi Giacomo, Silvestri Elena, Di Scala Gerardo, Palterer Boaz, Parronchi Paola. - In: INTERNAL AND EMERGENCY MEDICINE. - ISSN 1828-0447. - STAMPA. - 14:(2019), pp. 1-9. [10.1007/s11739-019-02150-z]

Intravenous immunoglobulin therapy: a snapshot for the internist.

Vitiello Gianfranco;Emmi Giacomo;Silvestri Elena;Di Scala Gerardo;Palterer Boaz;Parronchi Paola
2019

Abstract

Intravenous immunoglobulins are the cornerstone for the treatment of primary humoral immunodeficiencies and may be used for a great number of other autoimmune, neurological and hematological conditions as well. Given their wide application, the possibility of running across a patient who needs this kind of therapy is becoming increasingly common. Generally, intravenous immunoglobulins are well tolerated. However, numerous adverse reactions ranging from mild to severe have been reported and linked to patient- and product-related factors. For all these reasons, we present herein a comprehensive review of the on- and off-label applications of intravenous immunoglobulins and provide a guide for the internist how to minimize the risk of adverse reactions and manage them.
2019
14
1
9
Goal 3: Good health and well-being for people
Vitiello Gianfranco, Emmi Giacomo, Silvestri Elena, Di Scala Gerardo, Palterer Boaz, Parronchi Paola
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1165832
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