Obesity can be associated with increased cardio-metabolic risk, but some subjects with obesity do not show metabolic impairment and escape this association. Low grade inflammation (i.e., high sensitivity C-reactive protein [hsCRP] >3 mg/dl) is associated with high cardiovascular risk in obesity. We investigated renin-angiotensin system (RAS) activity in cultured circulating T-cell in subjects with obesity with and without angiotensin II (Ang II) stimulation in the presence or absence of low-grade inflammation.
T lymphocyte based renin angiotensin system in obesity / mirella coppo, manuela bandinelli, marco chiostri, loredana poggesi, maria boddi. - In: THE AMERICAN JOURNAL OF THE MEDICAL SCIENCES. - ISSN 0002-9629. - ELETTRONICO. - 358:(2019), pp. 51-58. [10.1016/j.amjms.2019.03.008]
T lymphocyte based renin angiotensin system in obesity
mirella coppo
;manuela bandinelliMembro del Collaboration Group
;marco chiostriMembro del Collaboration Group
;loredana poggesiConceptualization
;maria boddiConceptualization
2019
Abstract
Obesity can be associated with increased cardio-metabolic risk, but some subjects with obesity do not show metabolic impairment and escape this association. Low grade inflammation (i.e., high sensitivity C-reactive protein [hsCRP] >3 mg/dl) is associated with high cardiovascular risk in obesity. We investigated renin-angiotensin system (RAS) activity in cultured circulating T-cell in subjects with obesity with and without angiotensin II (Ang II) stimulation in the presence or absence of low-grade inflammation.
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