Background. Liver transplantation (LT) using grafts from non-heart-beating donors (NHBDs) has been shown to be a successful practice. Recently reported primary nonfunction rates are similar to those of LT using grafts from brain-dead donors. Method. We report the use of an NHBD liver, which was cut into a right-lobe graft and implanted as an auxiliary partial orthotopic liver transplant for acute liver failure in a 11-year-old child. The warm ischemia time was 21 minutes, and the cold ischemia was 8 hours. Results. Initial graft function was excellent, and the child is well, with normal liver function 2 months posttransplant. Conclusion. Reduction and splitting of livers from NHBDs for transplantation is a realistic option, provided there is careful selection of the graft.
Successful segmental auxiliary liver transplantation from a non-heart-beating donor: Implications for split-liver transplantation / Muiesan P; Girlanda R; Baker A; Rela M; Heaton N. - In: TRANSPLANTATION. - ISSN 0041-1337. - 75:(2003), pp. 1443-1445. [10.1097/01.TP.0000069024.86527.0B]
Successful segmental auxiliary liver transplantation from a non-heart-beating donor: Implications for split-liver transplantation
Muiesan P;
2003
Abstract
Background. Liver transplantation (LT) using grafts from non-heart-beating donors (NHBDs) has been shown to be a successful practice. Recently reported primary nonfunction rates are similar to those of LT using grafts from brain-dead donors. Method. We report the use of an NHBD liver, which was cut into a right-lobe graft and implanted as an auxiliary partial orthotopic liver transplant for acute liver failure in a 11-year-old child. The warm ischemia time was 21 minutes, and the cold ischemia was 8 hours. Results. Initial graft function was excellent, and the child is well, with normal liver function 2 months posttransplant. Conclusion. Reduction and splitting of livers from NHBDs for transplantation is a realistic option, provided there is careful selection of the graft.I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.