Our work aims to develop an alternative technology to overcome the many drawbacks and limitations of stitches and adhesive patches in wound healing, by the implementation of laser welding with biocompatible scaffolds. We report on electrospun fibers containing polysaccharidic components and hosting a variety of dyes, such as indocyanine green or plasmonic nanoparticles, that support different functions in different regimes of optical irradiation, i.e. watertight adhesion with cw light, and the controlled release of antimicrobial principles with pulsed light. We believe that our work will inspire new synergies at the crossroads between tissue engineering and biomedical optics.
New materials for laser welding of connective tissue and controlled release of antimicrobial principles / Ratto F., Aluigi A., Centi S., Milanesi A., Khlebtsov B. N., Khlebtsov N. G., Delfino V., Calonico C., Lo Nostro A., Magni G., Borri C., Cavigli L., Matteini P., Pini R., Rossi F.. - ELETTRONICO. - (2020), pp. 0-0. (Intervento presentato al convegno Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2020).
New materials for laser welding of connective tissue and controlled release of antimicrobial principles
Centi S.;Milanesi A.;Calonico C.;Lo Nostro A.;Magni G.;Matteini P.;
2020
Abstract
Our work aims to develop an alternative technology to overcome the many drawbacks and limitations of stitches and adhesive patches in wound healing, by the implementation of laser welding with biocompatible scaffolds. We report on electrospun fibers containing polysaccharidic components and hosting a variety of dyes, such as indocyanine green or plasmonic nanoparticles, that support different functions in different regimes of optical irradiation, i.e. watertight adhesion with cw light, and the controlled release of antimicrobial principles with pulsed light. We believe that our work will inspire new synergies at the crossroads between tissue engineering and biomedical optics.
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