our study in SMF indicates that female gender has a more indolent disease with a specific phenotype and better prognosis. This finding finally led to a more accurate definition of the natural history of the disease and drove the attention toward a careful interpretation of clinical trial results.
Gender effect on phenotype and genotype in patients with post-polycythemia vera and post-essential thrombocythemia myelofibrosis: results from the MYSEC project / Barraco D., Mora B., Guglielmelli P., Rumi E., Maffioli M., Rambaldi A., Caramella M., Komrokji R., Gotlib J., Kiladjian J.J., Cervantes F., Devos T., Palandri F., De Stefano V., Ruggeri M., Silver R.T., Benevolo G., Albano F., Merli M., Pietra D., et al.. - In: BLOOD CANCER JOURNAL. - ISSN 2044-5385. - ELETTRONICO. - 8:(2018), pp. 89-92. [10.1038/s41408-018-0128-x]
Gender effect on phenotype and genotype in patients with post-polycythemia vera and post-essential thrombocythemia myelofibrosis: results from the MYSEC project
Guglielmelli P.;Rotunno G.;Vannucchi A. M.;
2018
Abstract
our study in SMF indicates that female gender has a more indolent disease with a specific phenotype and better prognosis. This finding finally led to a more accurate definition of the natural history of the disease and drove the attention toward a careful interpretation of clinical trial results.
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