An altered (dysbiosis) and unhealthy status of the gut microbiota is usually responsible for a reduction of short chain fatty acids (SCFAs) concentration. SCFAs obtained from the carbohydrate fermentation processes are crucial in maintaining gut homeostasis and their determination in stool samples could provide a faster, reliable and cheaper method to highlight the presence of an intestinal dysbiosis and a biomarker for various gut diseases. We hypothesize that different intestinal diseases, such as celiac disease (CD), adenomatous polyposis (AP) and colorectal cancer (CRC) could display a particular fecal SCFAs' signature.

Evaluation and comparison of short chain fatty acids composition in gut diseases / Niccolai E.; Baldi S.; Ricci F.; Russo E.; Nannini G.; Menicatti M.; Poli G.; Taddei A.; Bartolucci G.; Calabro A.S.; Stingo F.C.; Amedei A.. - In: WORLD JOURNAL OF GASTROENTEROLOGY. - ISSN 1007-9327. - ELETTRONICO. - 25:(2019), pp. 5543-5558. [10.3748/wjg.v25.i36.5543]

Evaluation and comparison of short chain fatty acids composition in gut diseases

Niccolai E.;Baldi S.;Ricci F.;Russo E.;Menicatti M.;Taddei A.;Bartolucci G.;Calabro A. S.;Stingo F. C.;Amedei A.
2019

Abstract

An altered (dysbiosis) and unhealthy status of the gut microbiota is usually responsible for a reduction of short chain fatty acids (SCFAs) concentration. SCFAs obtained from the carbohydrate fermentation processes are crucial in maintaining gut homeostasis and their determination in stool samples could provide a faster, reliable and cheaper method to highlight the presence of an intestinal dysbiosis and a biomarker for various gut diseases. We hypothesize that different intestinal diseases, such as celiac disease (CD), adenomatous polyposis (AP) and colorectal cancer (CRC) could display a particular fecal SCFAs' signature.
2019
25
5543
5558
Niccolai E.; Baldi S.; Ricci F.; Russo E.; Nannini G.; Menicatti M.; Poli G.; Taddei A.; Bartolucci G.; Calabro A.S.; Stingo F.C.; Amedei A.
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1173756
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