Timing and significance of exercise-induced left ventricular outflow tract pressure gradients in hypertrophic cardiomyopathy

In Hypertrophic cardiomyopathy patients without outflow obstruction at rest, earlier onset of LV outflow tract gradients during physiologic exercise was associated with impaired exercise performance. These findings provide insights into the determinants of functional impairment in HC and support the potential value of exercise echocardiography in the clinical assessment of patients with this disease.