Compared with <1 in 200 otherwise healthy adults, QT prolongation (QTc > 480 ms) was present in 1 out of 8 patients with HCM. The QTc was partly reflective of the degree of cardiac hypertrophy and left ventricular outflow tract obstruction. Because of its pro-arrhythmic potential and its potential relevance to management and risk stratification, routine QTc assessment should be performed in patients with HCM, particularly when concomitant use of QT-prolonging medications is considered.

Prevalence and clinical correlates of QT prolongation in patients with hypertrophic cardiomyopathy / Johnson J.N.; Grifoni C.; Bos J.M.; Saber-Ayad M.; Ommen S.R.; Nistri S.; Cecchi F.; Olivotto I.; Ackerman M.J.. - In: EUROPEAN HEART JOURNAL. - ISSN 0195-668X. - STAMPA. - 32:(2011), pp. 1114-1120. [10.1093/eurheartj/ehr021]

Prevalence and clinical correlates of QT prolongation in patients with hypertrophic cardiomyopathy

Grifoni C.;Nistri S.;Cecchi F.;Olivotto I.;
2011

Abstract

Compared with <1 in 200 otherwise healthy adults, QT prolongation (QTc > 480 ms) was present in 1 out of 8 patients with HCM. The QTc was partly reflective of the degree of cardiac hypertrophy and left ventricular outflow tract obstruction. Because of its pro-arrhythmic potential and its potential relevance to management and risk stratification, routine QTc assessment should be performed in patients with HCM, particularly when concomitant use of QT-prolonging medications is considered.
2011
32
1114
1120
Johnson J.N.; Grifoni C.; Bos J.M.; Saber-Ayad M.; Ommen S.R.; Nistri S.; Cecchi F.; Olivotto I.; Ackerman M.J.
File in questo prodotto:
File Dimensione Formato  
QT-lungo EurHeart2011.pdf

Accesso chiuso

Tipologia: Pdf editoriale (Version of record)
Licenza: Tutti i diritti riservati
Dimensione 201.82 kB
Formato Adobe PDF
201.82 kB Adobe PDF   Richiedi una copia

I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1176062
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 88
  • ???jsp.display-item.citation.isi??? 75
social impact