Early response to ABVD, assessed with interim FDG-PET (iPET), is prognostic for classical Hodgkin's Lymphoma (cHL) and supports the use of response adapted therapy. The aim of this study was to identify a gene-expression profile on diagnostic biopsy to predict iPET positivity (iPET+).
A gene expression-based model to predict metabolic response after two courses of ABVD in Hodgkin Lymphoma patients / Luminari, Stefano; Donati, Benedetta; Casali, Massimiliano; Valli, Riccardo; Santi, Raffaella; Puccini, Benedetta; Kovalchuk, Sofya; Ruffini, Alessia; Fama, Angelo; Berti, Valentina; Fragliasso, Valentina; Zanelli, Magda; Vergoni, Federica; Versari, Annibale; Rigacci, Luigi; Merli, Francesco; Ciarrocchi, Alessia. - In: CLINICAL CANCER RESEARCH. - ISSN 1078-0432. - ELETTRONICO. - (2019), pp. clincanres.2356.2019-clincanres.2356.2019. [10.1158/1078-0432.CCR-19-2356]
A gene expression-based model to predict metabolic response after two courses of ABVD in Hodgkin Lymphoma patients
Santi, Raffaella;Puccini, Benedetta;Kovalchuk, Sofya;Berti, Valentina;Rigacci, Luigi;
2019
Abstract
Early response to ABVD, assessed with interim FDG-PET (iPET), is prognostic for classical Hodgkin's Lymphoma (cHL) and supports the use of response adapted therapy. The aim of this study was to identify a gene-expression profile on diagnostic biopsy to predict iPET positivity (iPET+).
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