Objective: To investigate the correlation of a history of lower urinary tract symptomatology during childhood with lower urinary tract dysfunction in young adult women. Subjects and Methods: This was a multicentre, prospective, case–control study conducted between April 2013 and November 2015. A total of 300 women, aged 18–40 years, participated. The case group comprised women attending urogynaecology clinics for various lower urinary tract complaints and the control group was recruited from a healthy population. Exclusion criteria were designed to avoid common causes of lower urinary tract dysfunction and symptoms and included diabetes mellitus, neurological disease and pelvic inflammatory disease. All women completed a self-administered 77-item questionnaire, exploring childhood urological and bowel history, as well as current urological, bowel and sexual symptoms. Statistical analysis was performed using chi-squared and Fisher's exact tests to compare categorical variables. Multivariate logistic regression models were fit for the prediction of the adult outcomes, incorporating as explanatory variables all those that showed a significant P value in bivariate analysis. P values < 0.05 were considered statistically significant. Results: Women with childhood urinary voiding and storage symptoms had a higher prevalence of these symptoms in adult life compared with women without such history. Women with urinary tract infections (UTIs) during childhood had a higher incidence of adult UTIs compared with women without this problem in childhood. Conclusions: Lower urinary tract dysfunction in childhood seems to ‘persist’ in young adult life but the implications of this finding in clinical practice need to be defined in future studies
Urological dysfunction in young women: an inheritance of childhood? / Costantini E.; Illiano E.; Giannitsas K.; Prestipino M.; Pastore A.L.; Carbone A.; Palleschi G.; Balsamo R.; Natale F.; Villari D.; Bini V.; Maruccia S.; Filocamo M.-T.; Zucchi A.. - In: BJU INTERNATIONAL. - ISSN 1464-4096. - ELETTRONICO. - 121:(2018), pp. 453-457. [10.1111/bju.14081]
Urological dysfunction in young women: an inheritance of childhood?
Villari D.;
2018
Abstract
Objective: To investigate the correlation of a history of lower urinary tract symptomatology during childhood with lower urinary tract dysfunction in young adult women. Subjects and Methods: This was a multicentre, prospective, case–control study conducted between April 2013 and November 2015. A total of 300 women, aged 18–40 years, participated. The case group comprised women attending urogynaecology clinics for various lower urinary tract complaints and the control group was recruited from a healthy population. Exclusion criteria were designed to avoid common causes of lower urinary tract dysfunction and symptoms and included diabetes mellitus, neurological disease and pelvic inflammatory disease. All women completed a self-administered 77-item questionnaire, exploring childhood urological and bowel history, as well as current urological, bowel and sexual symptoms. Statistical analysis was performed using chi-squared and Fisher's exact tests to compare categorical variables. Multivariate logistic regression models were fit for the prediction of the adult outcomes, incorporating as explanatory variables all those that showed a significant P value in bivariate analysis. P values < 0.05 were considered statistically significant. Results: Women with childhood urinary voiding and storage symptoms had a higher prevalence of these symptoms in adult life compared with women without such history. Women with urinary tract infections (UTIs) during childhood had a higher incidence of adult UTIs compared with women without this problem in childhood. Conclusions: Lower urinary tract dysfunction in childhood seems to ‘persist’ in young adult life but the implications of this finding in clinical practice need to be defined in future studiesFile | Dimensione | Formato | |
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