Abstract: OBJECTIVE: We carried out a propensity-score based analysis on early outcomes after coronary artery bypass grafting (CABG) in patients with or without peripheral vascular disease (PAD). METHODS: Eighteen thousand-three hundred-eleven patients undergoing isolated CABG between 1997 and 2017 were included into the study. Subjects with previous or concomitant vascular surgery were excluded. The main endpoints were death, stroke and limb ischemia requiring percutaneous or surgical revascularization. Sub-Group analyses were carried out to test the interaction of PAD with concomitant factors. RESULTS: The incidence of death was comparable in patients with or without PAD (p=0.06 and p=0.179, respectively). In contrast, PAD patients showed a higher incidence of stroke (p=0.04) acute kidney disease (p=0.003) and limb ischemia requiring intervention (p<0.001).The employment of off-pump or no-touch aortic techniques did not influence the effect of PAD on outcomes (all, p>0.05). In contrast, early mortality increased with PAD when the arteriopathy was associated to long CPB and CC times (both p<0.001) and postoperative low output syndrome (p=0.01). CONCLUSIONS: The presence of peripheral arterial disease increases independently of other factors the incidence of postoperative stroke, acute kidney disease and limb ischemia irrespective of the technique employed.In contrast, death was higher in PAD patients only when it was associated to postoperative low output syndrome, long cardiopulmonary bypass and aortic cross clamp times.

Outcomes Of Isolated Coronary Artery Bypass In Peripheral Artery Disease Patients / Massimo Bonacchi, Orlando Parise, Aleksander Dokollari, Giulia Chiuselli, Bruno Chiarello, Francesco Cabrucci, Edvin Prifti, Sandro Gelsomino,. - STAMPA. - (2019), pp. 0-3. ((Intervento presentato al convegno 5th International Coronary Congress tenutosi a New York nel 4-6 dicembre 2019.

Outcomes Of Isolated Coronary Artery Bypass In Peripheral Artery Disease Patients

Massimo Bonacchi
;
Giulia Chiuselli;CHIARELLO, BRUNO;CABRUCCI, FRANCESCO;Sandro Gelsomino
2019

Abstract

Abstract: OBJECTIVE: We carried out a propensity-score based analysis on early outcomes after coronary artery bypass grafting (CABG) in patients with or without peripheral vascular disease (PAD). METHODS: Eighteen thousand-three hundred-eleven patients undergoing isolated CABG between 1997 and 2017 were included into the study. Subjects with previous or concomitant vascular surgery were excluded. The main endpoints were death, stroke and limb ischemia requiring percutaneous or surgical revascularization. Sub-Group analyses were carried out to test the interaction of PAD with concomitant factors. RESULTS: The incidence of death was comparable in patients with or without PAD (p=0.06 and p=0.179, respectively). In contrast, PAD patients showed a higher incidence of stroke (p=0.04) acute kidney disease (p=0.003) and limb ischemia requiring intervention (p<0.001).The employment of off-pump or no-touch aortic techniques did not influence the effect of PAD on outcomes (all, p>0.05). In contrast, early mortality increased with PAD when the arteriopathy was associated to long CPB and CC times (both p<0.001) and postoperative low output syndrome (p=0.01). CONCLUSIONS: The presence of peripheral arterial disease increases independently of other factors the incidence of postoperative stroke, acute kidney disease and limb ischemia irrespective of the technique employed.In contrast, death was higher in PAD patients only when it was associated to postoperative low output syndrome, long cardiopulmonary bypass and aortic cross clamp times.
5th International Coronary Congress
5th International Coronary Congress
New York
4-6 dicembre 2019
Massimo Bonacchi, Orlando Parise, Aleksander Dokollari, Giulia Chiuselli, Bruno Chiarello, Francesco Cabrucci, Edvin Prifti, Sandro Gelsomino,
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2158/1178451
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact