G protein-coupled receptors (GPCRs) are the most common receptors on the surface of cardiomyocytes. GPCRs coupled to Gq play a central role in mediating the response of cardiac tissue to several hormones. Angiotensin-II (acting on the AT1 receptor), endothelin-1 (ETA receptor), and noradrenaline/adrenaline (alpha-adrenergic receptor) are the main hormones that share the intracellular signalling associated with Gq protein in the cardiomyocyte.

Cardiomyocyte-specific Gq signalling and arrhythmias: Novel insights from DREADD technology / Ferrantini C.; Coppini R.; Sacconi L.. - In: CARDIOVASCULAR RESEARCH. - ISSN 0008-6363. - ELETTRONICO. - 115:(2019), pp. 992-994. [10.1093/cvr/cvz052]

Cardiomyocyte-specific Gq signalling and arrhythmias: Novel insights from DREADD technology

Ferrantini C.;Coppini R.;
2019

Abstract

G protein-coupled receptors (GPCRs) are the most common receptors on the surface of cardiomyocytes. GPCRs coupled to Gq play a central role in mediating the response of cardiac tissue to several hormones. Angiotensin-II (acting on the AT1 receptor), endothelin-1 (ETA receptor), and noradrenaline/adrenaline (alpha-adrenergic receptor) are the main hormones that share the intracellular signalling associated with Gq protein in the cardiomyocyte.
2019
115
992
994
Ferrantini C.; Coppini R.; Sacconi L.
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1181438
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