Sodium-glucose cotransporter 2 inhibitors (SGLT2i) decreased serum uric acid in type 2 diabetes. Hyperuricemia is associated with an increased risk of nephrolithiasis. The present meta-analysis, performed on trials with duration ≥52 weeks in comparison with placebo or active comparators, suggests no effects of SGLT-2i on the risk of nephrolithiasis.
Nephrolithiasis and sodium-glucose co-transporter-2 (SGLT-2) inhibitors: A meta-analysis of randomized controlled trials / Cosentino C.; Dicembrini I.; Nreu B.; Mannucci E.; Monami M.. - In: DIABETES RESEARCH AND CLINICAL PRACTICE. - ISSN 0168-8227. - ELETTRONICO. - 155:(2019), pp. 0-0. [10.1016/j.diabres.2019.107808]
Nephrolithiasis and sodium-glucose co-transporter-2 (SGLT-2) inhibitors: A meta-analysis of randomized controlled trials
Dicembrini I.;Nreu B.;Mannucci E.;Monami M.
2019
Abstract
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) decreased serum uric acid in type 2 diabetes. Hyperuricemia is associated with an increased risk of nephrolithiasis. The present meta-analysis, performed on trials with duration ≥52 weeks in comparison with placebo or active comparators, suggests no effects of SGLT-2i on the risk of nephrolithiasis.I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.