The paper describes the scenario of FDG uptake by the diverse metabolic cancer cell subpopulations inside a proliferative tumor. Changes in pHe and lactate due to local modification (e.g. high interstitial pressure, local ischemia) may drive a continuous metabolic reprogramming limiting FDG uptake.
FDG uptake in cancer: a continuing debate / Silvia Peppicelli, Elena Andreucci, Jessica Ruzzolini, Francesca Bianchini, Lido Calorini. - In: THERANOSTICS. - ISSN 1838-7640. - ELETTRONICO. - 10:(2020), pp. 2944-2948.
FDG uptake in cancer: a continuing debate
Silvia Peppicelli;Elena Andreucci;Jessica Ruzzolini;Francesca Bianchini
;Lido Calorini
2020
Abstract
The paper describes the scenario of FDG uptake by the diverse metabolic cancer cell subpopulations inside a proliferative tumor. Changes in pHe and lactate due to local modification (e.g. high interstitial pressure, local ischemia) may drive a continuous metabolic reprogramming limiting FDG uptake.
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