Purpose: To evaluate the role of contrast-enhanced spectral mammography (CESM) in the post biopsy management of breast lesions classified as lesions of uncertain malignant potential (B3) by core needle biopsy and vacuum-assisted biopsy (VAB). Methods: The local ethics committee approved this retrospective study and for this type of study formal consent is not required. A total of 42 B3 lesions in 40 women aged 41–77 years were included in our study. All patients underwent CESM 2–3 weeks after the biopsy procedure and surgical excision was subsequently performed within 60 days of the CESM procedure. Three radiologists reviewed the images independently. The results were then compared with histologic findings. Results: The sensitivity, specificity, and positive and negative predictive values for confirmed demonstration of malignancy at CESM were 33.3%, 87.2%, 16.7%, and 94.4% for reader 1; 66.7%, 76.9%, 18.2%, and 96.7% for reader 2; 66.7%, 74.4%, 16.7%, and 96.7% for reader 3. Overall agreement on detection of malignant lesions using CESM among readers ranged from moderate to substantial (κ =.451–.696), for categorization of BPE from moderate to substantial (κ =.562–.711), and for evaluation of lesion intensity enhancement from fair to moderate (κ =.346–.459). Conclusion: In cases of Breast Imaging Reporting and Data System (BI-RADS) 1, BI-RADS 2, or BI-RADS 3 results at CESM, follow-up or VAB rather than surgical biopsy might be performed.

Role of contrast-enhanced spectral mammography in the post biopsy management of B3 lesions: Preliminary results / Bicchierai G.; Nori J.; De Benedetto D.; Boeri C.; Vanzi E.; Bianchi S.; Kaur Gill M.; Cirone D.; Miele V.. - In: TUMORI. - ISSN 0300-8916. - ELETTRONICO. - 105:(2019), pp. 378-387. [10.1177/0300891618816212]

Role of contrast-enhanced spectral mammography in the post biopsy management of B3 lesions: Preliminary results

Bicchierai G.;Nori J.;De Benedetto D.;Boeri C.;Vanzi E.;Bianchi S.;Cirone D.;Miele V.
2019

Abstract

Purpose: To evaluate the role of contrast-enhanced spectral mammography (CESM) in the post biopsy management of breast lesions classified as lesions of uncertain malignant potential (B3) by core needle biopsy and vacuum-assisted biopsy (VAB). Methods: The local ethics committee approved this retrospective study and for this type of study formal consent is not required. A total of 42 B3 lesions in 40 women aged 41–77 years were included in our study. All patients underwent CESM 2–3 weeks after the biopsy procedure and surgical excision was subsequently performed within 60 days of the CESM procedure. Three radiologists reviewed the images independently. The results were then compared with histologic findings. Results: The sensitivity, specificity, and positive and negative predictive values for confirmed demonstration of malignancy at CESM were 33.3%, 87.2%, 16.7%, and 94.4% for reader 1; 66.7%, 76.9%, 18.2%, and 96.7% for reader 2; 66.7%, 74.4%, 16.7%, and 96.7% for reader 3. Overall agreement on detection of malignant lesions using CESM among readers ranged from moderate to substantial (κ =.451–.696), for categorization of BPE from moderate to substantial (κ =.562–.711), and for evaluation of lesion intensity enhancement from fair to moderate (κ =.346–.459). Conclusion: In cases of Breast Imaging Reporting and Data System (BI-RADS) 1, BI-RADS 2, or BI-RADS 3 results at CESM, follow-up or VAB rather than surgical biopsy might be performed.
2019
105
378
387
Bicchierai G.; Nori J.; De Benedetto D.; Boeri C.; Vanzi E.; Bianchi S.; Kaur Gill M.; Cirone D.; Miele V.
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1190201
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