Dravet syndrome is a rare, treatment-resistant developmental epileptic encephalopathy characterised by multiple types of frequent, disabling seizures. Fenfluramine has been reported to have antiseizure activity in observational studies of photosensitive epilepsy and Dravet syndrome. The aim of the present study was to assess the efficacy and safety of fenfluramine in patients with Dravet syndrome.
Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised,double-blind, placebo-controlled trial / Lagae L, S.J., FAiRE DS Study Group. - In: THE LANCET. - ISSN 0099-5355. - ELETTRONICO. - 394:(2020), pp. 2243-2254. [10.1016/S0140-6736(19)32500-0]
Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised,double-blind, placebo-controlled trial
Guerrini R;
2020
Abstract
Dravet syndrome is a rare, treatment-resistant developmental epileptic encephalopathy characterised by multiple types of frequent, disabling seizures. Fenfluramine has been reported to have antiseizure activity in observational studies of photosensitive epilepsy and Dravet syndrome. The aim of the present study was to assess the efficacy and safety of fenfluramine in patients with Dravet syndrome.
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