We present the experimental implementation and validation of a phantom for diffuse optical imaging based on totally absorbing objects for which, in the previous paper [J. Biomed. Opt. 18(6), 066014, (2013)], we have provided the basic theory. Totally absorbing objects have been manufactured as black polyvinyl chloride (PVC) cylinders and the phantom is a water dilution of intralipid-20% as the diffusive medium and India ink as the absorber, filled into a black scattering cell made of PVC. By means of time-domain measurements and of Monte Carlo simulations, we have shown the reliability, the accuracy, and the robustness of such a phantom in mimicking typical absorbing perturbations of diffuse optical imaging. In particular, we show that such a phantom can be used to generate any absorption perturbation by changing the volume and position of the totally absorbing inclusion. © The Authors.

Phantoms for diffuse optical imaging based on totally absorbing objects, part 2: Experimental implementation / Martelli F.; Ninni P.D.; Zaccanti G.; Contini D.; Spinelli L.; Torricelli A.; Cubeddu R.; Wabnitz H.; Mazurenka M.; MacDonald R.; Sassaroli A.; Pifferi A.. - In: JOURNAL OF BIOMEDICAL OPTICS. - ISSN 1083-3668. - ELETTRONICO. - 19:(2014), pp. 076011-1-076011-10. [10.1117/1.JBO.19.7.076011]

Phantoms for diffuse optical imaging based on totally absorbing objects, part 2: Experimental implementation

Martelli F.
Supervision
;
Zaccanti G.;
2014

Abstract

We present the experimental implementation and validation of a phantom for diffuse optical imaging based on totally absorbing objects for which, in the previous paper [J. Biomed. Opt. 18(6), 066014, (2013)], we have provided the basic theory. Totally absorbing objects have been manufactured as black polyvinyl chloride (PVC) cylinders and the phantom is a water dilution of intralipid-20% as the diffusive medium and India ink as the absorber, filled into a black scattering cell made of PVC. By means of time-domain measurements and of Monte Carlo simulations, we have shown the reliability, the accuracy, and the robustness of such a phantom in mimicking typical absorbing perturbations of diffuse optical imaging. In particular, we show that such a phantom can be used to generate any absorption perturbation by changing the volume and position of the totally absorbing inclusion. © The Authors.
2014
19
076011-1
076011-10
Goal 3: Good health and well-being for people
Martelli F.; Ninni P.D.; Zaccanti G.; Contini D.; Spinelli L.; Torricelli A.; Cubeddu R.; Wabnitz H.; Mazurenka M.; MacDonald R.; Sassaroli A.; Pifferi A.
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1194315
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