Prolonged outbreak of New Delhi metallo-betalactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE), Tuscany, Italy, 2018 to 2019

Tavoschi, L.; Forni, S.; Porretta, A.; Righi, L.; Pieralli, F.; Menichetti, F.; Falcone, M.; Gemignani, G.; Sani, S.; Vivani, P.; Bellandi, T.; Tacconi, D.; Turini, L.; Toccafondi, G.; Privitera, G.; Lopalco, P.; Baggiani, A.; Gemmi, F.; Luchini, G.; Petrillo, M.; Roti, L.; Pezzotti, P.; Pantosti, A.; Iannazzo, S.; Mechi, M.; Rossolini, G. M.

doi:10.2807/1560-7917.ES.2020.25.6.2000085

In Tuscany, Italy, New Delhi metallo-beta-lactamaseproducing carbapenem-resistant Enterobacterales (NDM-CRE) have increased since November 2018. Between November 2018 and October 2019, 1,645 samples were NDM-CRE-positive: 1,270 (77.2%) cases of intestinal carriage, 129 (7.8%) bloodstream infections and 246 (14.9%) infections/colonisations at other sites. Klebsiella pneumoniae were prevalent (1,495; 90.9%), with ST147/NDM-1 the dominant clone. Delayed outbreak identification and response resulted in sustained NDM-CRE transmission in the North-West area of Tuscany, but successfully contained spread within the region.

Prolonged outbreak of New Delhi metallo-betalactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE), Tuscany, Italy, 2018 to 2019 / Tavoschi L.; Forni S.; Porretta A.; Righi L.; Pieralli F.; Menichetti F.; Falcone M.; Gemignani G.; Sani S.; Vivani P.; Bellandi T.; Tacconi D.; Turini L.; Toccafondi G.; Privitera G.; Lopalco P.; Baggiani A.; Gemmi F.; Luchini G.; Petrillo M.; Roti L.; Pezzotti P.; Pantosti A.; Iannazzo S.; Mechi M.; Rossolini G.M.. - In: EUROSURVEILLANCE. - ISSN 1025-496X. - ELETTRONICO. - 25:(2020), pp. 13-19. [10.2807/1560-7917.ES.2020.25.6.2000085]