Hyponatremia is the most common electrolyte disorder encountered in clinical practice and is associated with an increased risk of overall mortality in in-patients . The most common cause of hyponatremia is the syndrome of inappropriate antidiuresis (SIAD), which accounts for up to 40–50% of cases, but the prevalence may be higher in some pathological conditions, such as subarachnoid haemorrhage, traumatic brain injury, and pneumonia. Besides infec-tious diseases, several inflammatory conditions may be com-plicated by SIAD. In these situations, interleukin-6 (IL-6), released by monocytes and macrophages, plays a pathogenic role in causing electrolyte impairment by inducing the non-osmotic release of vasopressin

Hyponatremia, IL‑6, and SARS‑CoV‑2 (COVID‑19) infection: may all fit together? / A Berni, D Malandrino, G Parenti, M Maggi, L Poggesi, A Peri. - In: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION. - ISSN 0391-4097. - STAMPA. - 43:(2020), pp. 1137-1139. [10.1007/s40618-020-01301-w]

Hyponatremia, IL‑6, and SARS‑CoV‑2 (COVID‑19) infection: may all fit together?

D Malandrino;G Parenti;M Maggi;L Poggesi;A Peri
2020

Abstract

Hyponatremia is the most common electrolyte disorder encountered in clinical practice and is associated with an increased risk of overall mortality in in-patients . The most common cause of hyponatremia is the syndrome of inappropriate antidiuresis (SIAD), which accounts for up to 40–50% of cases, but the prevalence may be higher in some pathological conditions, such as subarachnoid haemorrhage, traumatic brain injury, and pneumonia. Besides infec-tious diseases, several inflammatory conditions may be com-plicated by SIAD. In these situations, interleukin-6 (IL-6), released by monocytes and macrophages, plays a pathogenic role in causing electrolyte impairment by inducing the non-osmotic release of vasopressin
2020
43
1137
1139
Goal 3: Good health and well-being for people
A Berni, D Malandrino, G Parenti, M Maggi, L Poggesi, A Peri
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Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1196327
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