Hepatic mesenchymal hamartoma and placental mesenchymal dysplasia: an association ever less rare; a focus on current Knowledge

Hepatic mesenchymal hamartoma (HMH) is a lesion that originates from the mesenchymal tissue of the portal tract and that in most cases manifests itself in the first three years of life. The placental mesenchymal dysplasia (PMD) is a rare anomaly characterized by placentomegaly with the presence of hydropic chorionic villous that resem- ble those of hydatiform mole. In literature there is only a few number of cases characterized by this association that have led to formulate the hypothesis of a common patho- genetic pathway to the two pathologies. This report wants to offer tools for a correct prenatal diagnosis and manage- ment of similar cases