Introducing PIONEER: a project to harness big data in prostate cancer research

Omar, M. I.; Roobol, M. J.; Ribal, M. J.; Abbott, T.; Agapow, P. -M.; Araujo, S.; Asiimwe, A.; Auffray, C.; Balaur, I.; Beyer, K.; Bernini, C.; Bjartell, A.; Briganti, A.; Butler-Ransohoff, J. -E.; Campi, R.; Cavelaars, M.; De Meulder, B.; Devecseri, Z.; Voss, M. D.; Dimitropoulos, K.; Evans-Axelsson, S.; Franks, B.; Fullwood, L.; Horgan, D.; Smith, E. J.; Kiran, A.; Kivinummi, K.; Lambrecht, M.; Lancet, D.; Lindgren, P.; Maclennan, S.; Maclennan, S.; Nogueira, M. M.; Moen, F.; Moinat, M.; Papineni, K.; Reich, C.; Reiche, K.; Rogiers, S.; Sartini, C.; Van Bochove, K.; Van Diggelen, F.; Van Hemelrijck, M.; Van Poppel, H.; Zong, J.; N'Dow, J.; Andersson, E.; Arala, H.; Auvinen, A.; Bangma, C.; Burke, D.; Cardone, A.; Casariego, J.; Cuperus, G.; Dabestani, S.; Esperto, F.; Fossati, N.; Fridhammar, A.; Gandaglia, G.; Tandefelt, D. G.; Horn, F.; Huber, J.; Hugosson, J.; Huisman, H.; Josefsson, A.; Kilkku, O.; Kreuz, M.; Lardas, M.; Lawson, J.; Lefresne, F.; Lejeune, S.; Longden-Chapman, E.; Mcvie, G.; Moris, L.; Mottet, N.; Murtola, T.; Nicholls, C.; Pang, K. H.; Pascoe, K.; Picozzi, M.; Plass, K.; Pohjanjousi, P.; Reaney, M.; Remmers, S.; Robinson, P.; Schalken, J.; Schravendeel, M.; Seisen, T.; Servan, A.; Shiranov, K.; Snijder, R.; Steinbeisser, C.; Taibi, N.; Talala, K.; Tilki, D.; Van Den Broeck, T.; Vassilev, Z.; Voima, O.; Vradi, E.; Waldeck, R.; Weistra, W.; Willemse, P. -P.; Wirth, M.; Wolfinger, R.; Kermani, N. Z.

doi:10.1038/s41585-020-0324-x

Prostate Cancer Diagnosis and Treatment Enhancement Through the Power of Big Data in Europe (PIONEER) is a European network of excellence for big data in prostate cancer, consisting of 32 private and public stakeholders from 9 countries across Europe. Launched by the Innovative Medicines Initiative 2 and part of the Big Data for Better Outcomes Programme (BD4BO), the overarching goal of PIONEER is to provide high-quality evidence on prostate cancer management by unlocking the potential of big data. The project has identified critical evidence gaps in prostate cancer care, via a detailed prioritization exercise including all key stakeholders. By standardizing and integrating existing high-quality and multidisciplinary data sources from patients with prostate cancer across different stages of the disease, the resulting big data will be assembled into a single innovative data platform for research. Based on a unique set of methodologies, PIONEER aims to advance the field of prostate cancer care with a particular focus on improving prostate-cancer-related outcomes, health system efficiency by streamlining patient management, and the quality of health and social care delivered to all men with prostate cancer and their families worldwide.

Introducing PIONEER: a project to harness big data in prostate cancer research / Omar M.I.; Roobol M.J.; Ribal M.J.; Abbott T.; Agapow P.-M.; Araujo S.; Asiimwe A.; Auffray C.; Balaur I.; Beyer K.; Bernini C.; Bjartell A.; Briganti A.; Butler-Ransohoff J.-E.; Campi R.; Cavelaars M.; De Meulder B.; Devecseri Z.; Voss M.D.; Dimitropoulos K.; Evans-Axelsson S.; Franks B.; Fullwood L.; Horgan D.; Smith E.J.; Kiran A.; Kivinummi K.; Lambrecht M.; Lancet D.; Lindgren P.; MacLennan S.; MacLennan S.; Nogueira M.M.; Moen F.; Moinat M.; Papineni K.; Reich C.; Reiche K.; Rogiers S.; Sartini C.; van Bochove K.; van Diggelen F.; Van Hemelrijck M.; Van Poppel H.; Zong J.; N'Dow J.; Andersson E.; Arala H.; Auvinen A.; Bangma C.; Burke D.; Cardone A.; Casariego J.; Cuperus G.; Dabestani S.; Esperto F.; Fossati N.; Fridhammar A.; Gandaglia G.; Tandefelt D.G.; Horn F.; Huber J.; Hugosson J.; Huisman H.; Josefsson A.; Kilkku O.; Kreuz M.; Lardas M.; Lawson J.; Lefresne F.; Lejeune S.; Longden-Chapman E.; McVie G.; Moris L.; Mottet N.; Murtola T.; Nicholls C.; Pang K.H.; Pascoe K.; Picozzi M.; Plass K.; Pohjanjousi P.; Reaney M.; Remmers S.; Robinson P.; Schalken J.; Schravendeel M.; Seisen T.; Servan A.; Shiranov K.; Snijder R.; Steinbeisser C.; Taibi N.; Talala K.; Tilki D.; Van den Broeck T.; Vassilev Z.; Voima O.; Vradi E.; Waldeck R.; Weistra W.; Willemse P.-P.; Wirth M.; Wolfinger R.; Kermani N.Z.. - In: NATURE REVIEWS. UROLOGY. - ISSN 1759-4812. - ELETTRONICO. - 17:(2020), pp. 351-361. [10.1038/s41585-020-0324-x]