Adjuvant chemotherapy is a standard treatment option for patients with stage III and high-risk stage II colon cancer. Sex is one of several factors responsible for the wide inter-patient variability in drug responses. Amalgamated data on the effect of sex on the toxicity of current standard adjuvant treatment for colorectal cancer are missing.
Sex and adverse events of adjuvant chemotherapy in colon cancer: an analysis of 34,640 patients in the ACCENT database / Wagner, Anna D; Grothey, Axel; Andre, Thierry; Dixon, Jesse G; Wolmark, Norman; Haller, Daniel G; Allegra, Carmen J; de Gramont, Aimery; VanCutsem, Eric; Alberts, Steven R; George, Thomas J; O'Connell, Michael J; Twelves, Christopher; Taieb, Julien; Saltz, Leonard B; Blanke, Charles D; Francini, Edoardo; Kerr, Rachel; Yothers, Greg; Seitz, Jean F; Marsoni, Silvia; Goldberg, Richard M; Shi, Qian. - In: JOURNAL OF THE NATIONAL CANCER INSTITUTE. - ISSN 0027-8874. - STAMPA. - (2021), pp. 0-0. [10.1093/jnci/djaa124]
Sex and adverse events of adjuvant chemotherapy in colon cancer: an analysis of 34,640 patients in the ACCENT database
Francini, EdoardoWriting – Review & Editing
;
2021
Abstract
Adjuvant chemotherapy is a standard treatment option for patients with stage III and high-risk stage II colon cancer. Sex is one of several factors responsible for the wide inter-patient variability in drug responses. Amalgamated data on the effect of sex on the toxicity of current standard adjuvant treatment for colorectal cancer are missing.
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