In the near future, the overlap of Coronavirus disease 2019 (COVID-19) and dengue epidemics is a concrete threat in tropical regions. Co-epidemics of COVID-19 and dengue could be an overwhelming challenge for health systems in low-and middle-income countries. In this work, we investigated potential serological cross-reactions between COVID-19 and dengue patients. Among 32 COVID-19 positive sera, no positive Dengue virus (DENV) IgG/IgM results were observed. On the other hand, one false-positive result was observed among 44 DENV-positive sera tested for COVID-19 antibodies with each of the two rapid tests used. Further data on accuracy of COVID-19 diagnostic test are urgently warranted.
Low risk of serological cross-reactivity between dengue and COVID-19 / Spinicci M.; Bartoloni A.; Mantella A.; Zammarchi L.; Rossolini G.M.; Antonelli A.. - In: MEMÓRIAS DO INSTITUTO OSWALDO CRUZ. - ISSN 1678-8060. - ELETTRONICO. - 115:(2020), pp. 1-2. [10.1590/0074-02760200225]
Low risk of serological cross-reactivity between dengue and COVID-19
Spinicci M.
;Bartoloni A.;Zammarchi L.;Rossolini G. M.;
2020
Abstract
In the near future, the overlap of Coronavirus disease 2019 (COVID-19) and dengue epidemics is a concrete threat in tropical regions. Co-epidemics of COVID-19 and dengue could be an overwhelming challenge for health systems in low-and middle-income countries. In this work, we investigated potential serological cross-reactions between COVID-19 and dengue patients. Among 32 COVID-19 positive sera, no positive Dengue virus (DENV) IgG/IgM results were observed. On the other hand, one false-positive result was observed among 44 DENV-positive sera tested for COVID-19 antibodies with each of the two rapid tests used. Further data on accuracy of COVID-19 diagnostic test are urgently warranted.
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