Behçet’s syndrome (BS) is a rare neutrophilic vasculitis characterized by arterial and venous events, uniquely treated by immunosuppressants rather than anticoagulants. We demonstrated in BS an impaired fibrinogen structure and fibrin susceptibility to plasmin-induced lysis, mainly due to an enhanced neutrophils reactive oxygen species (ROS) production, supporting the notion that BS is a model of inflammation-induced thrombosis .

Butyrate Rich Diets Improve Redox Status and Fibrin Lysis in Behçet's Syndrome / Emmi, Giacomo; Bettiol, Alessandra; Niccolai, Elena; Ramazzotti, Matteo; Amedei, Amedeo; Pagliai, Giuditta; Taddei, Niccolò; Sofi, Francesco; Fiorillo, Claudia; Prisco, Domenico; Becatti, Matteo. - In: CIRCULATION RESEARCH. - ISSN 0009-7330. - STAMPA. - 128:(2021), pp. 278-280. [10.1161/CIRCRESAHA.120.317789]

Butyrate Rich Diets Improve Redox Status and Fibrin Lysis in Behçet's Syndrome

Emmi, Giacomo
Writing – Original Draft Preparation
;
Bettiol, Alessandra
Formal Analysis
;
Niccolai, Elena
Investigation
;
Ramazzotti, Matteo
Formal Analysis
;
Amedei, Amedeo
Writing – Review & Editing
;
Pagliai, Giuditta
Investigation
;
Taddei, Niccolò
Writing – Review & Editing
;
Sofi, Francesco
Writing – Review & Editing
;
Fiorillo, Claudia
Writing – Review & Editing
;
Prisco, Domenico
Writing – Review & Editing
;
Becatti, Matteo
Writing – Original Draft Preparation
2021

Abstract

Behçet’s syndrome (BS) is a rare neutrophilic vasculitis characterized by arterial and venous events, uniquely treated by immunosuppressants rather than anticoagulants. We demonstrated in BS an impaired fibrinogen structure and fibrin susceptibility to plasmin-induced lysis, mainly due to an enhanced neutrophils reactive oxygen species (ROS) production, supporting the notion that BS is a model of inflammation-induced thrombosis .
128
278
280
Goal 3: Good health and well-being
Emmi, Giacomo; Bettiol, Alessandra; Niccolai, Elena; Ramazzotti, Matteo; Amedei, Amedeo; Pagliai, Giuditta; Taddei, Niccolò; Sofi, Francesco; Fiorillo, Claudia; Prisco, Domenico; Becatti, Matteo
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2158/1216570
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