We used a functional magnetic resonance imaging task with an event-related design of stimulus to explore the anticipated abnormally decreased blood oxygen level dependent effect in CADASIL. In CADASIL patients, an event-related Go/No-go task reveals a lower blood oxygen level dependent effect in the alerting network and areas involved in executive functions possibly reflecting the altered hemodynamic response secondary to small-vessel changes. Our observation extends the role of MR in demonstrating one of the fundamental pathophysiological changes of CADASIL

Functional Magnetic Resonance Imaging of Inhibitory Control Reveals Decreased Blood Oxygen Level Dependent Effect in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy / Gioele Gavazzi, Stefano Orsolini, Emilia Salvadori, Andrea Bianchi, Arianna Rossi, Ida Donnini, Valentina Rinnoci, Francesca Pescini, Stefano Diciotti, Maria Pia Viggiano, Mario Mascalchi, Leonardo Pantoni. - In: STROKE. - ISSN 0039-2499. - STAMPA. - 50:(2019), pp. 69-75. [10.1161/STROKEAHA.118.022923]

Functional Magnetic Resonance Imaging of Inhibitory Control Reveals Decreased Blood Oxygen Level Dependent Effect in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy

Gioele Gavazzi;Stefano Orsolini;Emilia Salvadori;Andrea Bianchi;Arianna Rossi;Ida Donnini;Valentina Rinnoci;Francesca Pescini;Stefano Diciotti;Maria Pia Viggiano;Mario Mascalchi;Leonardo Pantoni
2019

Abstract

We used a functional magnetic resonance imaging task with an event-related design of stimulus to explore the anticipated abnormally decreased blood oxygen level dependent effect in CADASIL. In CADASIL patients, an event-related Go/No-go task reveals a lower blood oxygen level dependent effect in the alerting network and areas involved in executive functions possibly reflecting the altered hemodynamic response secondary to small-vessel changes. Our observation extends the role of MR in demonstrating one of the fundamental pathophysiological changes of CADASIL
2019
50
69
75
Gioele Gavazzi, Stefano Orsolini, Emilia Salvadori, Andrea Bianchi, Arianna Rossi, Ida Donnini, Valentina Rinnoci, Francesca Pescini, Stefano Diciotti...espandi
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in FLORE sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificatore per citare o creare un link a questa risorsa: https://hdl.handle.net/2158/1221339
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 13
  • ???jsp.display-item.citation.isi??? 12
social impact