Outcomes of antenatally diagnosed exomphalos

Objective To determine outcomes for antenatally diagnosed exomphalos over an 11 year period. Method All cases diagnosed with exomphalos (January 1998–December 2008) in a fetal medicine unit at a tertiary unit were reviewed. Results 96 cases of exomphalos were diagnosed antenatally at 12–27 weeks. There was isolated exomphalos in 43 (44.8%) cases and other anomalies present in 53 (55.2%) cases. 66 women (68.8%) had karyotyping performed, demonstrating normal karyotype in 49 cases (74.2%), trisomy 18 in 13 cases (19.7%) and trisomy 13 in one case (1.5%). When other anomalies were present the karyotype was abnormal in 44.8%. Karyotype was abnormal in 8.3% of isolated exomphalos. 53 (55.2%) women opted for termination. In pregnancies terminated, 26.4% had a known chromosomal anomaly and 69.8% had other structural anomalies on scan. 43 (44.8%) women continued the …