Valacyclovir for prevention and treatment of fetal CMV infection: inclusion in the Law 648/96 list and launch of the Italian multicentre observational prospective study "MEGAL-ITALI"

given the current availability of an effective pharmacological intervention, it becomes impera- tive to re-evaluate the opportunity to introduce serological screening for CMV in pregnancy. In order to monitoring the effectiveness and the safety in the clinical practice of valacyclovir for the recently approved indication SIMIT, AMCLI and SIMP are launching a national observational study (MEGAL-ITALI) which is open to every health- care provider and institution in Italy willing to collaborate.