Mycoplasma pneumoniae-associated mucocutaneous disease in children: A case series with allergy workup in a tertiary care paediatric hospital

Mycoplasma pneumoniae (MP) infection is a common cause of community-acquired pneumonia in children sometimes associated with intriguing mucocutaneous manifestations variable in severity such as erythema multiforme (EM) or Stevens–Johnson syndrome (SJS).1 Various papers attempted to distinguish the clinical features of MP-associated diseases, but the topic is still confusing, ending in conflicting classifications.2-6 A systematic review suggested that they should be considered as distinct entities from the genuine drug-induced SJS, introducing the term ‘Mycoplasma-induced rash and mucositis’ (MIRM).7 Other authors used the expression ‘Mycoplasma pneumoniae-associated mucositis’ (MPAM) to distinguish a variant with isolated mucosal involvement without rash.8 Recently, MIRM have been included in a larger group called RIME (reactive infectious mucocutaneous eruption).