Discontinuation of antiepileptic drugs (AEDs) in seizure-free patients is an important goal because of possible long-term side effects and the social stigma burden of epilepsy. The purpose of this work was to assess seizure recurrence risk after suspension of AEDs, to evaluate predictors for recurrence, and to investigate the recovery of seizure control after relapse. In addition, the accuracy of a previously published prediction model of seizure recurrence risk was estimated.
Prediction of seizure recurrence risk following discontinuation of antiepileptic drugs / Contento, Margherita; Bertaccini, Bruno; Biggi, Martina; Magliani, Matteo; Failli, Ylenia; Rosati, Eleonora; Massacesi, Luca; Paganini, Marco. - In: EPILEPSIA. - ISSN 0013-9580. - STAMPA. - (2021), pp. 2159-2170. [10.1111/epi.16993]
Prediction of seizure recurrence risk following discontinuation of antiepileptic drugs
Contento, Margherita
;Bertaccini, Bruno;Biggi, Martina;Magliani, Matteo;Failli, Ylenia;Rosati, Eleonora;Massacesi, Luca
;Paganini, Marco
2021
Abstract
Discontinuation of antiepileptic drugs (AEDs) in seizure-free patients is an important goal because of possible long-term side effects and the social stigma burden of epilepsy. The purpose of this work was to assess seizure recurrence risk after suspension of AEDs, to evaluate predictors for recurrence, and to investigate the recovery of seizure control after relapse. In addition, the accuracy of a previously published prediction model of seizure recurrence risk was estimated.File | Dimensione | Formato | |
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