Variations in maxillary second molar position of untreated subjects with normal occlusions: A long-term observational study

Introduction: The purpose of the present study was to evaluate the long-term variations in maxillary second molar position in untreated subjects with normal occlusion. Setting and sample population: A sample of 39 subjects (18 females and 21 males) selected from the University of Michigan Growth Study (UMGS) was followed longitudinally with digital dental casts at 3 observation times: T1, when the maxillary permanent second molars were fully erupted, T2, last observation available in the longitudinal series (38 subjects), and T3, at least 20 years after T2 (12 subjects). Materials and methods: Digital measurements were recorded with an open-source software. Outcome variables were sagittal and transverse inclinations of the upper second molars. Two mixed-effect models were performed. Results: The maxillary second molars had a distolingual inclination at T1, T2 and T3. Sagittal and transverse inclination showed progressive significant uprighting from T1 through T3 (P <.001). From T1 to T2, the adjusted difference in sagittal crown inclination was 8.0° (95% CI from 6.5° to 9.6°; P <.001). From T2 to T3, the adjusted difference was 5.5° (95% CI from 3.0° to 8.1°; P <.001). From T1 to T2, the adjusted difference in transverse crown inclination was 1.9° (95% CI from 0.4° to 3.5°; P =.011). From T2 to T3, the adjusted difference was 6.0° (95% CI from 3.4° to 8.5°; P <.001). Conclusions: Along with age, maxillary second molars showed a progressive significant uprighting with a decrease in the distal and lingual inclinations.