New Insight into the Role of Adenosine in Demyelination, Stroke and Neuropathic Pain

Our group of research has a long-time experience in studying the role/s of adenosine P1 receptors in health and disease conditions of the central nervous system (CNS). The effects of adenosine were investigated in our laboratory by the use of in vitro or in vivo models. In most recent years, main topics of our research concerned the study of adenosine and its receptors in the physiological processes of myelination and in pathological conditions of ischemia. Most recently, the group addressed the study of adenosine-mediated mechanisms in pain control. Here, we are going to summarize our recent findings.